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RESEARCH

ISCN Online


The Standard Reference Combining ISCN and HGVS Nomenclature.

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The Indispensable Reference

The International System for Human Cytogenomic Nomenclature (ISCN) is an indispensable reference volume for human cytogeneticists, molecular biologists, technicians, and students for the interpretation and communication of human cytogenomic nomenclature.

With ISCN Online you always have an updated copy of the ISCN at your disposal.

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What's New in ISCN 2024?

Interview with Dr. Ros Hastings

Apart from making regular corrections and updates, those more fundamental changes were implemented:

  • A new nomenclature is introduced specifically for genomic mapping in the diagnostic setting taking elements of karyotyping, microarray and region-specific nomenclature to describe the observed structural and copy-number variation.
  • An introductory chapter summarizes the generic rules that are applicable across all techniques.
  • Additional nomenclature examples have been added to most chapters and now include ISCN for chimeras, moles and chromoanasynthesis.
  • The RSA chapter has been expanded to include nomenclature for targeted chromosome analysis, targeted microarray analysis, fusion genes, expansion repeats and methylation assays for imprinting.
  • The ISCN examples are numbered for ease of reference.
  • Finally, the Committee identified the need to streamline the nomenclature so it is consistent across the different technologies.

Anytime, Everywhere

The recent pandemic has made work from home for many of us the default work place. It is therefore practical to have ISCN online and available anytime and everywhere.

  • Interact with the authors of ISCN and the community in the forum.
  • Search engine that makes access to the text easier to practitioners.
  • The latest nomenclature changes from the previous ISCN edition highlighted.
  • Access to all previous ISCN editions for consultation purposes.
  • Supplemented with tools helping the ISCN specialists in their daily work.

About ISCN 2024 Online

The International System for Human Cytogenomic Nomenclature (ISCN) offers standard nomenclature that is used to describe any genomic rearrangement identified by techniques ranging from karyotyping to FISH, microarray, various region-specific assays, and DNA sequencing.

Suggestions from the international cytogenetics community have been reviewed by the Standing Committee, an international group of experts – nominated and elected by their peers.

Is the ISCN 2024 Online Identical to the Print Edition?

  • Yes, both contain exactly the same text.
  • The online version text will stay identical with the latest printed version, guaranteeing no versioning or confusion between the online and printed edition.
  • The HGVS nomenclature will follow the latest guidelines available at:
    https://varnomen.hgvs.org/

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USD 95.00

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USD 250.00

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* Availability of the perpetual (lifetime) access model: Lifetime Access for ISCN 2024 is defined as timely unlimited access to iscn.karger.com from the day of subscribing to the moment when this service will end to exist. Karger reserves the right to discontinue access for customers with Lifetime Access Rights for ISCN 2024, if the respective customer fails to use the content in compliance with the requirements of the applicable Terms & Conditions.
 

How to Access ISCN Online

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